The present volume covers all aspects of pain research, starting with a history of pain and moving through invertebrate model systems and the human genetics of pain and functional imaging. Chapters include the role of ion channels, the opioid system, the immune and sympathetic systems, as well as the mechanisms that transform acute to chronic pain. Migraine and the interplay between sleep and pain are discussed. New technology in the form of transgenic animals, chemogenetics, optogenetics, and proteomic analyses are also covered.
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